BIOTREND Chemicals, LLC

GST-fusion of I1aPP2A (GLO140, this page). Maintains all known activities of native protein tested to date. Effective for binding and pull-down studies. Purity > 90% by SDS-PAGE. Apparent Mr ~ 58-kDa.

Distinct insulin-stimulated cytosolic protein kinase which phosphorylates eIF-4E (GLO118, kinase substrates) at physiological sites. Regulates protein synthesis and numerous other cellular processes. Source bovine kidney. Purity > 90% by SDS-PAGE. Apparent Mr ~ 45-kDa. Specific activity ~ 17,000...

The p21-activated p65PAK protein kinase is involved in cytoskeleton organization, apoptosis and signal transduction processes. The enzyme has been found associated with PP2A (GLO130-132, protein phosphatases) and ribosomal protein S6 kinase. The catalytic domain of the enzyme is produced in...

Distinct MAPK family member. MAPK is involved in regulating numerous cellular processes including cell growth and differentiation. In contrast to other MAPK's, MBPK-1 is not inactivated by protein tyrosine phosphatases. MBPK-1 and MBPK-2 phosphorylate and activate cPK (GLO117, this page). Source...

The A (also termed PR65) subunit of PP2A (GLO130-GLO132, protein phosphatases) serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit, generating functionally diverse heterotrimers of the phosphatase. The A subunit also serves to...

AGlu416 contains a mutation in a basic motif that is an important determinant for the interaction of the A subunit and the catalytic subunit of PP2A (GLO130-GLO132, protein phosphatases). The AGlu416 preparations can be used as control in reconstitution studies and for further delineating the...

Almost over 1.600 different products labeled with [3H] / [14C] / [125I] from Acacetine to Xylose are available in our database and cover Signal Transduction products like cAMP/cGMP RIA, Ion Channel products, Second Messengers, Phosphoinositides and Bioactive Lipids

Mitochondial enzymes regulated by reversible phosphorylation. Catalyzes the oxidative decarboxylation of the branched-chain a-keto acids derived from the essential amino acids, leucine, isoleucine and valine. Purified preparations undergo phosphorylation because endogenous kinase is tightly...

Cap-binding protein involved in rate limiting step in protein synthesis. Undergoes phosphorylation at Ser209 in response to growth factors and other extracellular stimuli. Occurs as a complex with eIF-4BP's and as part of the eIF-4F complex. Source human recombinant. Purity > 90% by SDS-PAGE....

Scarce enzyme which undergoes rapid autophosphorylation and dramatic (15-30-fold) activation. The enzyme phosphorylates and inactivates PP2A (GLO130-132, protein phosphatases). AK is involved in cytoskeleton organization and other signal transduction processes. The purified preparations appear...